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Dose: 0.25mg daily for weeks 1-2, increased to 0.5mg daily for weeks 3-6 Administration: Subcutaneous injection, rotating between deltoid area and upper chest near the shoulder Duration: 6 weeks total Supporting therapy: Light stretching daily, avoided overhead movements until week 4 Three months out from finishing the protocol, my shoulder still feels solid

Similarly, no clinically significant ARA 290related alterations of baseline biochemical (electrolytes, calcium, liver, kidney or pancreas) or hematological (erythrocyte, thrombocyte or leukocyte) parameters were observed

Stem Cells 26 , 10651073 (2008)

One hypothesis for RA pathogenesis is that the disease begins in genetically predisposed individuals at mucosal sites (i.e., oral cavity, lung, gut) as a consequence of the interaction between a dysbiotic microbiota and the mucosal immune system, and then transitions to synovitis [8]

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