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We evaluate gait mechanics, foot structure, imaging (if needed), and contributing factors like tight calves or hormone imbalance

Jolkinolide B targets thioredoxin and glutathione systems to induce ROS-mediated paraptosis and apoptosis in bladder cancer cells

Free radicals can cause DNA damage, impairing cellular function or killing cells altogether

They also integrate upstream signals such as mTOR, IFN-, and ERK1/2 to fine-tune autophagic responses to metabolic and infectious stress

The elevated production of OPT is typically observed in APAP-overdosed mice [144], in patients with hepatic injury [142], and in fasted mice [145]