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These radicals can directly catalyze the oxidation of polyunsaturated fatty acid (PUFA) in the cytosol and plasma membrane under the action of lipoxygenase (LOX), generating a large amount of lipid ROS

Exposure to PM2.5 aggravates Parkinsons disease via inhibition of autophagy and mitophagy pathway

doi: 10.1039/d0cc00470g 37 LiuKHuaSSongL

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Thermosensitive in situ hydrogels of rivastigmine-loaded lipid-based nanosystems for nose-to-brain delivery: characterisation, biocompatibility, and drug deposition studies