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Along the years, the studies on the HU model have shown that various proteins involved in the control of sarcolemma excitability, calcium ion homeostasis, energy metabolism, and contractile machinery undergo changes in the expression, turnover, and activity in accord with the entering of the slow muscle into a fast program [111, 113117]

The top 5 regulons with the highest regulon specificity scores (RSS) in the control group and the PD-1 inhibitor group, respectively, are shown in Figures 4A, B

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Previous studies have demonstrated that the use of RXR partial agonists can reduce eosinophilic airway inflammation, a condition mediated, in part, by the chemoattractant activity of CCL11 60

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