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M.van den HoutA.HandelsR.BosI.van der FlierW

Physiological role of ROS in sperm function

[DOI] [PubMed] [Google Scholar] 18.Roos W.P., Krumm A

Notably, these developmental outcomes correlate with adverse effects on offspring mitochondrial function, including impaired complex I activity, shifts in the NADH/NAD + ratio, and disrupted cellular metabolism that persist into adulthood and correlate with accelerated biological aging

Additional information Graham, Nicholas A, Tahmasian, Martik, Kohli, Bitika, Komisopoulou, Evangelia, Zhu, Maggie, Vivanco, Igor, Teitell, Michael A, Wu, Hong, Ribas, Antoni, Lo, Roger S, Mellinghoff, Ingo K, Mischel, Paul S, Graeber, Thomas G, (2012) Glucose deprivation activates a metabolic and signaling amplification loop leading to cell death