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What makes a P450 tick

Specifically, intrinsic resistance is mainly caused by existing factors (e.g., gene mutations), while acquired resistance is caused by changes in tumor cells during treatment, including drug target expression, post-translational modification, and activation of bypass signaling (Holohan et al., 2013
Al-Serri A, Anstee QM, Valenti L et al (2012) The SOD2 C47T polymorphism influences NAFLD fibrosis severity: evidence from case-control and intra-familial allele association studies

Berberine: a novel therapeutic strategy for cancer

Vzina FA, Cantin AM (2018) Antioxidants and chronic obstructive pulmonary disease