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The build-up of ROS induces ER stress, causing the release of damage-associated molecular patterns (DAMPs) like calreticulin, ATP and high mobility group box 1 [261, 262]

Among the differentially expressed genes in MCF7 cells, decreased expression of PDK1 and upregulation of CDKN1A were observed

[DOI] [PubMed] [Google Scholar] 22.Yang T, Zelikin AN, Chandrawati R

[DOI] [PubMed] [Google Scholar] 22.Shibaguchi T., Yamaguchi Y., Miyaji N., Yoshihara T., Naito H., Goto K., Ohmori D., Yoshioka T., Sugiura T

Prior to the identification and study of GHK-Cu, research into tissue regeneration and skin remodeling relied primarily on isolated growth factors and nonspecific biochemical agents
