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MCAS can contribute to symptoms of excess histamine including: Fatigue Itching Hives Mood changes Asthma and wheezing Gastrointestinal distress diarrhea, bloating, nausea A few potential triggers of MCAS include: Stress Fatigue Diet Medications antibiotics, narcotics, contrast dyes, NSAIDs Mold Infection Lyme disease Environmental toxins such as heavy metals Exercise Contributing Factors to Histamine Intolerance There are several contributing factors to histamine intolerance your diet plays a role as well as stress levels and your gut health

These processes modulate lymphocyte proliferation and T cell activation (42, 46)