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To prevent hypertension, modifying various components of the diet, such as lowering salt and sugar intake, may be a key step in lowering high blood pressure (6)

RANKL binds to its receptor, namely, RANK, on osteoclast precursors and activates downstream signaling cascades, including nuclear factor kappa light chain enhancer of activated B cells (NF-B) and nuclear factor of activated T cells 1 (NFATc1), which promote precursor differentiation into mature, bone-resorbing osteoclasts and enhance their resorptive activity

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