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Description
Topical application of TRF (5 mg/cm 2 ) on depilated dorsal skin of healthy or diabetic mice markedly induced epidermal hair follicle development and early anagen induction, as evidenced by change of skin color from pink to black
Safety Information Do not exceed the recommended dosage
Toxicol Pathol
doi: 10.1046/j.1523-1747.2003.12056.x
Activation of mTORC1 leads to S6K1-mediated destabilization of insulin receptor substrate 1 (IRS1) and subsequent inhibition of IR and IGF-1R signaling [56], providing a negative feedback loop to downregulate AKT (Figure 1)
