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Understanding these mechanisms highlights the need to diagnose and treat B12 deficiency
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Modulate oxidative stress and increase cell longevity in research models through antioxidant-related pathways
In contrast, late-stage DKD is characterized by the accumulation of M2 macrophages (53), which promotes fibrogenesis through TGF-1-induced collagen synthesis and the activation of myofibroblasts, ultimately resulting in glomerulosclerosis and tubulointerstitial fibrosis
