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Feron et al., 1991), though few quantitative data are available
lanes 2 and 7, 1 day p.i
The combined depletion of GPX4 and the inducer of ferroptosis, PUFAPL, works synergistically to decrease the susceptibility of cancer cells to ferroptosis
It is well known that the onset of ferroptosis requires elevated levels of ferrous ions, which induce lipid peroxidation and ultimately result in cell death
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