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Many preclinical studies have shown that ROCK inhibitors alleviate pulmonary fibrosis through a variety of potential mechanisms [201]
Feb 2015;33(2):179-185
[DOI] [PMC free article] [PubMed] [Google Scholar] 93.Kaushik M.K., Kaul S.C., Wadhwa R., Yanagisawa M., Urade Y
A.BharadwajP
307 Besides, lactate and H+ ions exported to the TME impair immune surveillance of effector T cells and NK cells by respectively inhibiting glycolytic flux, granzyme B and IFN- secretion
