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were the first to identify the MET oncogene in 1984

This reveals a critical principle: for predicting the clinical outcome of protein-binding drug interactions, understanding the drug's extraction ratio is more important than simply knowing its degree of protein binding

Multi-week culture studies examining collagen, elastin, and proteoglycan gene expression often require repeat dosing of cultures across several passages, which draws down stock material more quickly than a single-endpoint assay

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Neuronal network oscillations in neurodegenerative diseases