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First, overexpression of the alsin long isoform protects against motor neuron toxicity induced by expression of A4T, or mutant SOD1 G85R or SOD1 G93A (Kanekura et al., 2004)

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[DOI] [PubMed] [Google Scholar] 6.Bajuri M.Y., Nordin A

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1