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This hypothesis is supported by several studies that have shown supplementation with SAM improves depressive symptoms (104-107)

My B12 levels remain low despite supplements

Consulting with a healthcare professional or sleep specialist can provide further guidance and personalized recommendations
4 Therefore, it carries a Category 2 bulk drug substance restriction

Disclose use to your GP or pharmacist without delay, and seek urgent medical attention via NHS 111 or 999 if you experience severe abdominal pain, persistent vomiting, dehydration, or symptoms of low blood sugar
