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Description
Naunyn-Schmiedeberg's Arch Pharmacol 399 , 1298313008 (2026)
Despite advances in targeting the KRAS protein directly or indirectly [2, 3] and the advent of immunotherapy [4], effective therapies for KRAS -mutant lung cancer remain elusive [5, 6], arguing for a better understanding of KRAS -driven tumorigenesis and the development of novel therapeutic strategies to combat the disease
Indeed, TBK1 stimulation upon xenophagy induction causes a significant reduction in IRGQ-GABARAPL2 endogenous foci measured with proximity ligation assays (PLA) (Figs
Local or systemic administration of Coenzyme Q10 during treatment helps reduce inflammation in periodontal tissues [55]
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