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Analysis of cell migration indicate that both p407 and the designed composition stimulate migration of HaCaT keratinocytes in vitro

Activating kinase domain mutations have subsequently been identified in a small number of other cancers

doi:10.1016/j.niox.2017.02.012 37

Moreover, the simulations confirmed that the Cagri P37 had weaker interactions with the ECDs leading to greater uncoupling of the peptide C-terminus from the ECDs (Supplementary Movie 1, Supplementary Tables 4, 5), and parallel increases in the dynamics of the peptide as it engaged with the CTR TM bundle, including F23

5-alpha reductase is the enzyme involved in DHT production