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doi: 10.1016/j.chemosphere.2016.09.056 190 WangY.XieR.LiQ.DaiF.LanG.ShangS.et al

Pharmacology 1:8289 Bertelli G, Gozza A, Forno GB, Vidili MG, Silvestro S, Venturini M, Dini D (1995) Topical dimethyl sulfoxide for the prevention of soft tissue injury after extravasation of vesicant cytotoxic drugs: a prospective clinical study

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it involves systematic checks for both expected and unexpected physiological changes
