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This review suggests the need for conducting clinical trials to evaluate the therapeutic potential of this bioactive compound (Hussain et al., 2022)
found that although androgen deprivation therapy inhibited the expression of renal glutaminase (KGA) in the GLS1 subtype, the expression of glutaminase C (GAC) was upregulated in tumor cells, which is an androgen-independent GLS1 subtype with stronger enzymatic activity

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doi: 10.3390/molecules27217644 108

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