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Footnotes * These authors contributed equally to this work Check the online version for the most updated information on this article, online supplements, and information on authorship & disclosures: www.haematologica.org/content/105/4/937 Funding MUM acknowledges funding from the Deutsche Forschungsgemeinschaft (SFB1036, SFB1118)

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doi: 10.1001/jama.2024.2315 2 TianJZhangDYaoXHuangYLuQ

Mild soreness or redness at the injection site is possible, but this typically resolves quickly and doesnt interrupt normal activities 3

Interestingly, macroscopic, histopathological examination and mucin content were in harmony with previous results, where pre-treatment with Piog, Ligu, and (Piog+Ligu) showed a declined mucosal injury as evidenced by the remarkable decrease of the ulcer area percentage by 62.3%, 38.7%, and 91.2%, respectively, compared to the ethanol-ulcerated group
