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doi: 10.1016/j.scitotenv.2020.144103 201 YoshimotoN.InoueE.SaitoK.YamayaT.TakahashiH

& Robertson, S
W.OshiroM

Mechanistically, it could be because PI3K activates AKT via downstream molecules, and AKT activates mTOR by phosphorylation

Immunostaining for PCNA also showed that treatment with insulin and IGF-1 increased PCNA positive cell numbers in the cultured metatarsal bone sections (Figure 1e and 1f)
