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Description
Author Contributions Conceptualization, G.C

2-OH Metabolites CYP1a1 is the enzyme responsible for the metabolism of E1 to 2-OH-E1 and E2 to 2-OH-E2

In case of sample size of the included RCTs, considering a type one error () of 5% and power of 80 or 90%, along with HOMA-IR, TG, hs-CRP and progesterone as the key outcome variables, sample size for each intervention group was calculated by the use of the proposed formula for parallel clinical trials

Nishikawa et al., 2017
Cytokine changes after a marathon race
