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Epithelial integrity, junctional complexes, and biomarkers associated with intestinal functions

Currently, clinical trials are investigating efficacy of CB-839 treatment in AML (NCT02071927) ( 5 Conclusions Considering our results and those of previous studies, we suggest that CLL cells can efficiently rewire their amino-acid and glucose metabolism to evade glutaminase inhibition

This was observed in platelet-derived growth factor-induced activation of asthmatic human bronchial smooth muscle cells ( KCa 3.1 Blocking may at least partially prevent ASM reconfiguration ( Hypertrophic and hyperplastic ASM cells exhibit metabolic changes, including increased glutamine metabolism, impaired fatty acid oxidation (FAO), and reduced ATP levels

PMID: 11765069

Randomized, double-blind, placebo-controlled trial of oral aloe vera gel for active ulcerative colitis