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The FDA-approved CSF1R inhibitor PLX3397 (pexidartinib) has demonstrated clinical efficacy in reducing TAM-mediated immunosuppression, and early-phase trials have evaluated its combination with ICIs to further enhance immune responses (162)
An immunohistochemical study on alpha-ketoglutarate dehydrogenase complex in Parkinsons disease
Systemic inflammasome activation and pyroptosis associate with the progression of amnestic mild cognitive impairment and Alzheimers disease
112 SheldonA
Microglial hexokinase 2 deficiency increases ATP generation through lipid metabolism leading to -amyloid clearance
