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TMAO also activates metabolic dysfunction through bile acid metabolism

In one of the earliest reports of the biocatalytic synthesis of ACE inhibitors, the chiral side chain of captopril and zofenopril were prepared by the lipase PS-30 (a Burkolderia cepacia lipase) catalyzed stereoselective esterification of racemic 3-benzoylthio-2-methylpropanoic acid in non- aqueous conditions (Patel et al., 1992)

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From the cover: correlations between apolipoprotein E 4 gene dose and brain-imaging measurements of regional hypometabolism
