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Both proteins act on the activation of transcription factors, such as JNK and AP-1, and it leads to the transcription of cell proliferation-related genes

Valkanova V, Ebmeier KP, Allan CL (2013)

Sun, X.Q

Metabolism plays a pivotal role in the aging process, and disruptions in metabolic pathways are often associated with age-related diseases

All of these ROS-related processes contribute to the development of hypertension (Figure 1)