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Doxorubicin was injected after the third measurement (16 minutes) and the resulting changes in PPR and OCR were measured for a further 20 measurements (over 150 minutes) yielding the basal response

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Desikan SP, Senapati J, Jabbour E, Abuasab T, Short N, Tang G, Wang S, Kebriaei P, Kadia T, Borthakur G , Ravandi F, Roberts K, Mullighan C, Konopleva M, Kantarjian H, Jain N

Approach stacks as exploratory and proceed carefully until robust human data emerge

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