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10.1007/s00330-004-2338-9 Garnier R, Boudignat O, Fournier PE: Valproate poisoning

Therefore, it has been investigated in ME/CFS and a positive treatment response was reported with low dose naltrexone (LDN) (3.04.5 mg/day) in 73.9% of the patients (218 ME/CFS patients) regarding improvement in their vigilance/alertness, as well as improved physical and cognitive performance
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& Perlman, S

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