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These are significant exemptions, and they are what make patient-specific compounding legally viable
SatoTakeda M., Ihn H., Ohashi J., et al., The human Histocompatibility Leukocyte Antigen (HLA) Haplotype Is Associated With the Onset of Postherpetic Neuralgia After herpes Zoster, Pain 110, no

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The population with multiple generations per year would more likely develop resistance to a pesticide because there would be more selection cycles (chances) to select for or to raise the percentage of resistant ones in the final population
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