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VEGFR2 activation can also stimulate angiogenesis - the formation of new blood vessels - which is essential for tissue repair and regeneration
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Among these latter, non-alcoholic fatty liver disease (NAFLD), characterized by lipid accumulation in hepatocytes, in the absence of alcohol abuse or other steatogenic factors, is one of the most prevalent

Since serum MMA evaluation can better define the cobalamin status, it should be routinely performed in the clinical setting, although wide dissemination of this approach will not be possible without validating the methodologies already present in veterinary laboratories
