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The Tim-AIII-HSP90 complex, in turn, interacts with GPX4, thus inhibiting the function of GPX4, likely by further ubiquitination and degradation of GXP4, and further inducing ferroptosis

J Neuropathol Exp Neurol 67:10551062 Kubat GB, Picone P (2024) Skeletal muscle dysfunction in amyotrophic lateral sclerosis: a mitochondrial perspective and therapeutic approaches
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With the FDAs decision, Cyltezo (adalimumab-adbm) can now be made available to patients with rheumatoid and psoriatic arthritis, ankylosing spondylitis, Crohns disease, ulcerative colitis, plaque psoriasis, and juvenile idiopathic arthritis who have a prescription for Humira (adalimumab)
