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This makes it particularly relevant in experimental models focused on targeted metabolic processes

Gradual dose reduction rather than abrupt cessation may improve weight maintenance, though evidence is limited

For the expression of ChR2, eYFP, or hM4D(Gi), For expressing ChR2, eYFP, or hM4D(Gi) the microinjection was performed unilaterally in the LH (from bregma (mm): AP -1.3, ML 1.0, and from dura (mm): DV -5.5)

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Mechanism of Action AOD-9604 targets adipose (fat) tissue through two key processes: Stimulates Lipolysis It activates 3-adrenergic receptors on fat cells, which signal the breakdown of stored triglycerides into free fatty acids