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Around 22.1% of older adults with mild dementia and 11.6% of those with moderate dementia also experience major depressive disorder [494]

As tau becomes hyperphosphorylated, its capacity to support microtubule assembly and stability diminishes, resulting in increased levels of unbound tau that may aggregate into tangles (if not secreted or degraded in the lysosome) [107]

A., Nanji, A

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Structure of the blood-brain barrier and its role in the transport of amino acids