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Here, we performed in-depth metabolic profiling of CMV-specific CD8 + T cells in patients who are immunocompromised and show the development of metabolic dysregulation at the transcriptional, protein, and functional level of CMV-specific CD8 + T cells in KTRs with noncontrolled CMV infection

Hill, T

AOD-9604 s selective mechanism functions regardless of baseline body composition, making it potentially effective even in relatively lean individuals

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These bispecific constructs, characterized by their small size, high solubility and extended half-life facilitated by the integration of an albumin-specific sdAb, have demonstrated potent cytotoxicity against tumor cells, exceeding the ADCC of Daratumumab [94]