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analyzed the effects of Isatuximab, the second anti-CD38 reagent approved by the FDA, on NK cells, which express CD16, a low affinity FcR ( Overall, these results suggest that some of the therapeutic actions of the antibody are mediated by direct signaling through the CD38 molecule, without the effects driven by FcRs, at least in the NK cells tested in vitro

Doctors said she had suffered a cardiac arrest, which occurs when an irregular heart rhythm causes the heart to stop

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Cecal mass did not significantly differ between groups (Supplementary Table S2)

Paresthesias and gait disturbances may begin to improve within two weeks, although full recovery can take several months