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Specifically, while Nrf2 activation is protective in acute MIRI, its sustained or non-selective overactivation may promote cancer cell proliferation and drug resistance by regulating the expression of antioxidant genes, thereby helping cancer cells resist oxidative damage caused by chemotherapy drugs and enhancing their survival capabilities (Nezu and Suzuki, 2021

Furthermore, a systematic review and meta-analysis found that zinc supplementation can alleviate depressive symptoms in patients undergoing antidepressant treatment (Da Silva et al., 2021)

Ferroptosis: molecular mechanisms and health implications

Anti-caking agent: Vegetable magnesium stearate

2005, London EA: The environment as an etiologic factor in autism: a new direction for research