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Infections Infections can also play a role in disrupting the intestinal barrier

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Dosing of Lcarnitine for VPAinduced toxicity Schiavo et al

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Chronic exposure to sertraline was shown to down-regulate expression of drug- and arachidonic acid-metabolizing enzymes in hepatic tissue, indicating that patients using this drug may be at risk of hepatotoxicity with reduced capacity to metabolize drugs and fatty acids (Almansour et al

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Symptoms may include severe abdominal pain, particularly in the upper right area, nausea, vomiting, and fever

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