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Metabolic flexibility or adaptation by cancer cells, as well as reduced antitumor immunity, may be unwanted consequences of inhibiting glutamine metabolism

Immune suppressive mechanisms in the tumor microenvironment

We're talking about kojic acid, a naturally-derived ingredient

This activation may be influenced by the addition of heterocyclic compounds (e.g
Furthermore, compared to healthy tissue-derived MSCs, tumor tissue-retained MSCs were found to exhibit unique expression profiles and significant tumor-promoting properties (125)