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According to the American Association of Clinical Endocrinologists and American College of Endocrinology (AACE/ACE) Obesity Clinical Practice Guidelines, all patients undergoing weight loss therapy should be monitored for mood disorders, depression, and suicidal ideation

However, rapid escalation should only be done under medical supervision to avoid side effects like nausea and dizziness

There is no official link between standard B12 supplementation and serious adverse effects in individuals with normal kidney and liver function

Funding This study received funding from the Center for Dermal Research (CDR) at Rutgers, The State University of New Jersey, 145 Bevier Road, Piscataway, NJ 08854

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