glutamate glutamine glutathione and related compounds - an overview Astrocyte glutamine is essential to
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Merola AA, Hayer TR (eds.) pp
Furthermore, disrupted calcium oscillations amplify energy crises: while physiological oscillations optimize TCA cycle efficiency via pyruvate dehydrogenase phosphatase activation, sustained pathological calcium signaling uncouples ATP synthesis from oxidative phosphorylation, accelerating cardiomyocyte apoptosis [81]
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