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Metabolically, persistent hyperglycemia upregulates glucose transporter-1 (GLUT1), reinforcing a self-perpetuating TGF-1GLUT1 signaling loop in mesangial cells that promotes abnormal extracellular matrix (ECM) accumulation, primarily of collagen and fibronectin (8)

NFE2L2: nuclear factor erythroid 2-related factor 2

Since the needle and tubing remain attached to the vein for a short duration, the chances of infections after IV push injections are minimal

10.4161/viru.22913 43 McCallA

Histone deacetylase inhibitor depsipeptide (FK228) induces apoptosis through histone acetylation and upregulation of Annexin A1 in AML1-ETO expressing Kasumi-1 cells