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It also interacts with the hypothalamic-pituitary-adrenal (HPA) axis to regulate stress hormone levels, making it beneficial for individuals dealing with sleep disturbances caused by stress or irregular schedules
Clinicians should be aware that creatinine-based eGFR may underestimate true kidney function in creatine users
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They are not a recommendation, and there is no modern, well-powered, FDA-recognized human trial that establishes a clinically validated dose
