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The methyltransferase domain of DNMT1 is an essential domain in acute myeloid leukemia independent of DNMT3A mutation

Thanwisate, T., Siriwanarangsun, P., Piyaselakul, S., Tharmviboonsri, T

doi: 10.1038/s41467-019-12896-x, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 4.Huang HT, Cheng TL, Lin SY, Ho CJ, Chyu JY, Yang RS, et al

The solution inside these prefilled pens is described in the official prescribing information as "clear, colorless to slightly yellow." Most users report that the liquid looks completely clear, like water, though a very faint yellow tint is within normal specifications

These processes are attributed to dysregulated autophagy and heightened TGF- signaling, ultimately resulting in adhesions that hinder tendon gliding functionality