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NAC has been purported to possess anti-inflammatory properties that include inhibiting activation and translocation of NF-B, which results in decreased production of TNF-, IL-1, and IL-6 [1]

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and 3) the authors did not verify the values of other vitamin B 12 biomarkers, such as MMA

The primary preclinical evidence comes from mouse studies showing reduced body weight and adipose mass in diet-induced obese mice (2018), improved grip strength in aged mice (2024), and beneficial microbiome changes when combined with caloric restriction (2022)

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