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The compound demonstrates exceptional target selectivity, with no inhibition of related methyltransferases (DNMT1, PRMT3, COMT) or NAD+ salvage enzymes (NAMPT, SIRT1) at concentrations up to 600 M

doi: 10.3389/fncel.2025.1512591 Received 16 October 2024 Accepted 29 January 2025 Published 12 February 2025 Volume 19 - 2025 Edited by Donato Zipeto, University of Verona, Italy Reviewed by Pablo Trindade, Federal University of Rio de Janeiro, Brazil Mingzi Zhang, University of Southern California, United States Updates Copyright 2025 Goshi, Lam, Bogguri, George, Sebastian, Cadena, Leon, Hum, Weilhammer, Fischer and Enright

By stimulating collagen synthesis and reorganizing damaged tissue fibers, the skin begins to appear plumper, more supple, and younger over time

For longer-term laboratory storage, freezing at approximately 20C is commonly referenced in research settings to help maintain compound integrity

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