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Description
J Invest Dermatol (2021) 141(9):220818.e14
They shield neural circuits from chronic stress, reduce maladaptive stress responses, and aid in reestablishing normal hypothalamic signaling
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[30] One of the most potent flavonoids in senotherapy, fisetin, when administered late in life in wild type mice, reduced senescence burden across multiple organs in vivo , improved tissue homeostasis, alleviated age-related pathologies and led to increased median and maximum lifespan
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