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It was originally suggested that inactivation of cytAspAT by -chloro-l-alanine is due to modification of a lysine residue by aminoacrylate (Morino et al., 1974)
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In human clinical trials, individuals taking ME-3 achieved a 49% increase in the ratio of reduced to oxidized glutathione
"Alpha-Ketoglutarate dietary supplementation to improve health in humans." Nutrition
Ramesh R, Manurung Y, Ma KH, Blakely T Jr., Won S, Moreno-Ramos OA, et al
