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People who eat a well-balanced diet that includes foods rich in vitamin B12, usually dont need to take additional B12

Upon entering the cell, two mechanisms are present to bind metals: specific chaperones that deliver essential metals directly to their cellular site of action [49,50], and chelators that neutralize and sequester excess free metal ions [51,52]
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Each compound should be reconstituted separately unless experimental design specifies otherwise

Endocrinology 156 , 39843995 (2015)
