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Nephrology 23, 867875

Kratom alkaloids are renowned for their ability to bind a wide range of peripheral and central nervous system receptors [43], including serotonin receptors [44, 45]
Calpains can alter synaptic plasticity by degrading membrane proteins such as glutamate receptors and transporters and can also modulate the function of protein kinases and phosphates

The copper complex is photosensitive
